Recent Updates
![]() |
LOGIQA: a database dedicated to long-range genome interactions quality assessment
posted on May 17, 2016 BMC Genomics 16 May 2016 | |
Abstract Proximity ligation-mediated methods are essential to study the impact of three-dimensional chromatin
organization on gene programming. Albeit significant progress has been made in the development of computational
tools that assess long-range chromatin interactions, next to nothing is known about the quality of the generated
datasets. We have developed LOGIQA (www.ngs-qc.org/logiqa), a database hosting quality scores for long-range
genome interaction assays, accessible through a user-friendly web-based environment. Currently, LOGIQA harbors QC scores for >900 datasets, which provides a global view of their relative quality
and reveals the impact of genome size, coverage and other technical aspects. LOGIQA provides a user-friendly dataset
query panel and a genome viewer to assess local genome-interaction maps at different resolution and
quality-assessment conditions. LOGIQA is the first database hosting quality scores dedicated to long-range chromatin interaction
assays, which in addition provides a platform for visualizing genome interactions made available by the
scientific community. |